Ontology highlight
ABSTRACT:
SUBMITTER: Tomlinson IP
PROVIDER: S-EPMC2816642 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
Tomlinson I P M IP Dunlop M M Campbell H H Zanke B B Gallinger S S Hudson T T Koessler T T Pharoah P D PD Niittymäki I I Tuupanen S S Aaltonen L A LA Hemminki K K Lindblom A A Försti A A Sieber O O Lipton L L van Wezel T T Morreau H H Wijnen J T JT Devilee P P Matsuda K K Nakamura Y Y Castellví-Bel S S Ruiz-Ponte C C Castells A A Carracedo A A Ho J W C JW Sham P P Hofstra R M W RM Vodicka P P Brenner H H Hampe J J Schafmayer C C Tepel J J Schreiber S S Völzke H H Lerch M M MM Schmidt C A CA Buch S S Moreno V V Villanueva C M CM Peterlongo P P Radice P P Echeverry M M MM Velez A A Carvajal-Carmona L L Scott R R Penegar S S Broderick P P Tenesa A A Houlston R S RS
British journal of cancer 20091117 2
It is now recognised that a part of the inherited risk of colorectal cancer (CRC) can be explained by the co-inheritance of low-penetrance genetic variants. The accumulated experience to date in identifying these variants has served to highlight difficulties in conducting statistically and methodologically rigorous studies and follow-up analyses. The COGENT (COlorectal cancer GENeTics) consortium includes 20 research groups in Europe, Australia, the Americas, China and Japan. The overarching goa ...[more]