Ontology highlight
ABSTRACT:
SUBMITTER: Toivola DM
PROVIDER: S-EPMC2843093 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Trends in cell biology 20100104 2
Intermediate filament (IF) proteins and heat shock proteins (HSPs) are large multimember families that share several features, including protein abundance, significant upregulation in response to a variety of stresses, cytoprotective functions, and the phenocopying of several human diseases after IF protein or HSP mutation. We are now coming to understand that these common elements point to IFs as important cellular stress proteins with some roles akin to those already well-characterized for HSP ...[more]