Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

3-Hydroxy-adamantane-1-acetic acid.

ABSTRACT: The crystal structure of the title adamantane derivative, C(12)H(18)O(3), has been determined by X-ray diffraction. The structure is stabilized by inter-molecular O-H?O hydrogen bonds, forming a chain.

SUBMITTER: Geng XH

PROVIDER: S-EPMC2960632 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

3-Hydroxy-adamantane-1-acetic acid.

Geng Xiao-Hong XH Kong Li-Chun LC Feng Yun-Long YL

Acta crystallographica. Section E, Structure reports online 20080806 Pt 9

The crystal structure of the title adamantane derivative, C(12)H(18)O(3), has been determined by X-ray diffraction. The structure is stabilized by inter-molecular O-H⋯O hydrogen bonds, forming a chain. ...[more]

PMID: 21201702

Similar Datasets

2-(4-Hydroxy-phen-yl)acetic acid-4,4'-bipyridine (1/1).

Project description:In the acid mol-ecule of the title complex, C(10)H(8)N(2)·C(8)H(8)O(3), the acetyl C-C-C-O torsion angle is -32.1?(3)°, and in the mol-ecule of the base, the dihedral angle between the two pyridine rings is 23.41?(10)°. In the crystal structure, inter-molecular O-H?N hydrogen bonds link the acid and the base mol-ecules into a one-dimensional triple-helix framework extended along the b axis.

| S-EPMC2979409 | biostudies-literature

[1-(4-Hydroxy-phen-yl)-1H-tetra-zol-5-ylsulfan-yl]acetic acid.

Project description:The title compound, C(9)H(8)N(4)O(3)S, shows a layer structure constructed from inter-molecular O-H⋯O and O-H⋯N hydrogen bonds. Inter-atomic distances suggest that extensive, but not uniform, π-electron delocalization is present in the tetra-zole rings and extends over the exocyclic C-S bond.

| S-EPMC2959972 | biostudies-literature

acetic acid bacteria

Project description:acetic acid bacteria

| PRJNA288385 | ENA

Miscellaneous Acetic Acid Bacteria

Project description:A miscellaneous collection of acetic acid bacteria Genome sequencing and assembly

| PRJNA638503 | ENA

Maleopimaric acid acetic acid solvate.

Project description:The title compound, C(24)H(32)O(5)·C(2)H(4)O(2), is a derivative of abietic acid. The two fused and unbridged cyclo-hexane rings have chair conformations and the anhydride ring is planar. Of the other three six-membered rings, two have boat conformations and one has a twist-boat conformation. The crystal structure is stabilized by inter-molecular O-H?O and C-H?O hydrogen bonds.

| S-EPMC2969235 | biostudies-literature

(5-Hydroxy-4-oxo-2-styryl-4H-pyridin-1-yl)-acetic Acid Derivatives as Multifunctional Aldose Reductase Inhibitors.

Project description:As rate-limited enzyme of polyol pathway, aldose reductase (ALR2) is one of the key inhibitory targets for alleviating diabetic complications. To reduce the toxic side effects of the inhibitors and to decrease the level of oxidative stress, the inhibitory selectivity towards ALR2 against detoxicating aldehyde reductase (ALR1) and antioxidant activity are included in the design of multifunctional ALR2 inhibitors. Hydroxypyridinone derivatives were designed, synthesized and evaluated their inhibitory behavior and antioxidant activity. Notably, {2-[2-(3,4-dihydroxy-phenyl)-vinyl]-5-hydroxy-4-oxo-4H-pyridin-1-yl}-acetic acid (7l) was the most potent, with IC50 values of 0.789 μM. Moreover, 7l showed excellent selectivity towards ALR2 with selectivity index 25.23, which was much higher than that of eparlestat (17.37), the positive control. More significantly, 7l performed powerful antioxidative action. At a concentration of 1 μM, phenolic compounds 7l scavenged DPPH radical with an inhibitory rate of 41.48%, which was much higher than that of the well-known antioxidant Trolox, at 11.89%. Besides, 7l remarkably suppressed lipid peroxidation with a rate of 88.76% at a concentration of 100 μM. The binding mode derived from molecular docking proved that the derivatives were tightly bound to the activate site, suggesting strongly inhibitory action of derivatives against ALR2. Therefore, these results provided an achievement of multifunctional ALR2 inhibitors capable with potency for both selective ALR2 inhibition and as antioxidants.

| S-EPMC7663616 | biostudies-literature

Cytenamide acetic acid solvate.

Project description:IN THE CRYSTAL STRUCTURE OF THE TITLE COMPOUND (SYSTEMATIC NAME: 5H-dibenzo[a,d]cyclo-hepta-triene-5-carboxamide ethanoic acid solvate), C(16)H(13)NO·C(2)H(4)O(2), the cytenamide and solvent mol-ecules form a hydrogen-bonded R(2) (2)(8) dimer motif, which is further connected to form a centrosymmetric double ring motif arrangement. The cycloheptene ring adopts a boat conformation and the dihedral angle between the least-squares planes through the two aromatic rings is 54.7?(2)°.

| S-EPMC2961612 | biostudies-literature

Arabidopsis: Control- vs. acetic acid treatment

Project description:Comparing Arabidopsis plants gene expresion in normal conditions (control) with acetic acid treated plants (acetic). Plants were grown on liquid MS media for 13 days, then they were transfered to MS liquid media (control) or MS+3,5 acetic acid (acetic) for two hours.

2011-12-30 | GSE29259 | GEO

Acetic Acid Bacteria and Cellulose

Project description:Acetic Acid Bacteria and Cellulose

| PRJEB28689 | ENA

2-(Benzene-sulfonamido)acetic acid.

Project description:The title compound, C(8)H(9)NO(4)S, is of inter-est as a precursor to biologically active sulfur-containing heterocyclic cmpounds. The crystal structure displays the classical O-H?O inter-molecular hydrogen bonding typical for carboxylic acids forming dimers. Symmetry-related dimers are, in turn, linked through head-to-tail pairs of inter-molecular N-H?O inter-actions, giving rise to a zigzag chain along the c axis.

| S-EPMC2959830 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data