Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

N-(2-Phenyl-imidazo[1,2-a]pyridin-3-yl)acetamide.

ABSTRACT: The crystal structure of the title compound, C(15)H(13)N(3)O, consists of columns of mol-ecules that are inter-connected by N-H?N hydrogen bonds in the direction of the b axis. The torsion angle between the imidazo[1,2-a]pyridine ring system and the phenyl ring is 9.04?(5)°.

SUBMITTER: Anaflous A

PROVIDER: S-EPMC2961311 | biostudies-literature | 2008 Apr

REPOSITORIES: biostudies-literature

ACCESS DATA

Json Xml

Publications

N-(2-Phenyl-imidazo[1,2-a]pyridin-3-yl)acetamide.

Anaflous Abderrahmane A Albay Hanane H Benchat Nour-Eddine NE El Bali Brahim B Dušek Michal M Fejfarová Karla K

Acta crystallographica. Section E, Structure reports online 20080426 Pt 5

The crystal structure of the title compound, C(15)H(13)N(3)O, consists of columns of mol-ecules that are inter-connected by N-H⋯N hydrogen bonds in the direction of the b axis. The torsion angle between the imidazo[1,2-a]pyridine ring system and the phenyl ring is 9.04 (5)°. ...[more]

PMID: 21202407

Similar Datasets

Crystal structure of (E)-4-[N-(7-methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)carboximido-yl]phenol.

Project description:The mol-ecule of the title compound, C21H17N3O, is built up from fused five- and six-membered rings connected to a methyl group, a phenyl ring and an (imino-meth-yl)phenol group. The fused ring system is almost planar (r.m.s. deviation = 0.031 Å) and forms dihedral angles of 64.97 (7) and 18.52 (6)° with the phenyl ring and the (imino-meth-yl)phenol group, respectively. In the crystal, centrosymmetric mol-ecules are linked by pairs of C-H⋯π inter-actions into dimeric units, which are further connected by O-H⋯N hydrogen bonds to form layers parallel to (101).

| S-EPMC4647394 | biostudies-literature

Crystal structure and Hirshfeld surface analysis of N-(tert-but-yl)-2-(phenyl-ethyn-yl)imidazo[1,2-a]pyridin-3-amine.

Project description:The bicyclic imidazo[1,2-a]pyridine core of the title compound, C19H19N3, is relatively planar with an r.m.s. deviation of 0.040 Å. The phenyl ring is inclined to the mean plane of the imidazo[1,2-a]pyridine unit by 18.2 (1)°. In the crystal, mol-ecules are linked by N-H⋯H hydrogen bonds, forming chains along the c-axis direction. The chains are linked by C-H⋯π inter-actions, forming slabs parallel to the ac plane. The Hirshfeld surface analysis and fingerprint plots reveal that the crystal structure is dominated by H⋯H (54%) and C⋯H/H⋯C (35.6%) contacts. The crystal studied was refined as an inversion twin.

| S-EPMC6775750 | biostudies-literature

N-(4-Chloro-pyridin-2-yl)-N-(4-methyl-phenyl-sulfon-yl)acetamide.

Project description:The crystal structure of the title compound, C(14)H(13)ClN(2)O(3)S, features a three-dimensional network stabilized by inter-molecular C-H?O hydrogen bonds between the mol-ecules. The 4-methyl-phenyl-sulfonyl ring forms a dihedral angle of 30.6?(1)° with the 4-chloro-pyridine ring.

| S-EPMC3011710 | biostudies-literature

2-(Carb-oxy-meth-yl)imidazo[1,2-a]pyridin-1-ium chloride.

Project description:In the crystal structure of the title salt, C(9)H(9)N(2)O(2) (+)·Cl(-), the cations and anions are linked into chains parallel to [021] by O-H?Cl and N-H?Cl hydrogen bonds.

| S-EPMC3569747 | biostudies-literature

Crystal structure of (5-methyl-imidazo[1,2-a]pyridin-2-yl)methanol.

Project description:In the title compound, C9H10N2O, the imidazo[1,2-a]pyridine moiety is approximately planar (r.m.s. deviation = 0.024 Å). The methanol group is nearly perpendicular to its mean plane as indicated by the C-C-C-O and N-C-C-O torsion angles of 80.04 (16) and -96.30 (17)°, respectively. In the crystal, mol-ecules are linked by O-H⋯N hydrogen bonds, forming inversion dimers with an R (2) 2(10) ring motif. The dimers are liked via C-H⋯O hydrogen bonds, enclosing R (2) 2(10) ring motifs and forming ribbons along [201]. The ribbons are linked via a number of π-π inter-actions [centroid-centroid distances vary from 3.4819 (8) to 3.7212 (8) Å], forming a three-dimensional structure.

| S-EPMC4257347 | biostudies-literature

[5-(2-Fur-yl)-6-nitro-1,2,3,5,6,7-hexa-hydro-imidazo[1,2-a]pyridin-8-yl](phen-yl)methanone.

Project description:In the title compound, C(18)H(17)N(3)O(4), the furyl and phenyl rings are inclined at almost right angles [85.77 (7) and 63.25 (7)°, respectively] to the central imidazo[1,2-a]pyridinyl unit. The structure displays both inter- and intra-molecular N-H⋯O hydrogen bonding.

| S-EPMC2969857 | biostudies-literature

6-Bromo-imidazo[1,2-a]pyridin-8-amine.

Project description:The title compound, C(7)H(6)BrN(3), crystallizes with three independent mol-ecules in the asymmetric unit. The mol-ecules are approximately planar (r.m.s. deviations for all non-H atoms = 0.016, 0.023 and 0.024?Å). The primary amine groups show pyramidal coordination. In the crystal, adjacent mol-ecules are linked by N-H?N hydrogen bonds. For two independent mol-ecules, the amine groups are hydrogen-bond donors via one H atom to one acceptor atom, whereas for the third independent mol-ecule, the amine group is a hydrogen-bond donor to two acceptor atoms.

| S-EPMC3247577 | biostudies-literature

1-Methyl-3-(4-chloro-benzo-yl)imidazo[1,2-a]pyridin-1-ium-2-olate.

Project description:In the mol-ecule of the title compound, C(15)H(11)ClN(2)O(2), the nine-membered heterobicycle is approximately planar [largest deviation from least-squares plane = 0.012?(2)?Å] and forms a dihedral angle of 51.14?(8)° with the plane of the 4-chloro-phenyl group. There is a non-classical intra-molecular hydrogen bond between the pyridine ?-H atom and the O atom of the benzoyl group. The crystal structure is stabilized by weak C-H?O and C-H?Cl inter-actions involving the 'olate' O atom and the Cl atom attached to the benzoyl group as acceptors.

| S-EPMC3201236 | biostudies-literature

6-Bromo-1-(1,2-propadien-yl)-3-(2-propyn-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one.

Project description:The reaction of propargyl bromide and 6-bromo-1,3-dihydro-imidazo[4,5-b]pyridin-2-one in refluxing dimethyl-formamide yields the title compound, C(12)H(8)BrN(3)O, which features nitro-gen-bound propadienyl and propynyl substituents. The imidazolopyridine fused ring is planar (r.m.s. deviation = 0.012?Å); the propadienyl chain is coplanar with the fused ring as it is conjugated with it, whereas the propynyl chain is not as the nitro-gen-bound C atom is a methyl-ene linkage. The acetyl-enic H atom is hydrogen bonded to the carbonyl O atom of an adjacent mol-ecule, forming a helical chain runnning along the b axis.

| S-EPMC2983773 | biostudies-literature

Crystal structure and Hirshfeld surface analysis of two imidazo[1,2-a]pyridine derivatives: N-tert-butyl-2-(4-meth-oxy-phen-yl)-5-methyl-imidazo[1,2-a]pyridin-3-amine and N-tert-butyl-2-[4-(di-methyl-amino)-phen-yl]imidazo[1,2-a]pyridin-3-amine.

Project description:In the title imidazo[1,2-a]pyridine derivatives, N-tert-butyl-2-(4-meth-oxy-phen-yl)-5-methyl-imidazo[1,2-a]pyridin-3-amine, C19H23N3O, (I), and N-tert-butyl-2-[4-(di-methyl-amino)-phen-yl]imidazo[1,2-a]pyridin-3-amine, C19H24N4, (II), the 4-meth-oxy-phenyl ring in (I) and the 4-(di-methyl-amino)-phenyl ring in (II) are inclined to the respective imidazole rings by 26.69?(9) and 31.35?(10)°. In the crystal of (I), mol-ecules are linked by N-H?N hydrogen bonds, forming chains propagating along the [001] direction. The chains are linked by C-H?? inter-actions, forming layers parallel to the (010) plane. In (II), the crystal packing also features N-H?N hydrogen bonds, which together with C-H?N hydrogen bonds link mol-ecules to form chains propagating along the c-axis direction. The chains are linked by C-H?? inter-actions to form layers parallel to the (100) plane. Inversion-related layers are linked by offset ?-? inter-actions [inter-centroid distance = 3.577?(1)?Å]. The inter-molecular inter-actions of both compounds were analyzed using Hirshfeld surface analysis and two-dimensional fingerprint plots.

| S-EPMC6281107 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data