Ontology highlight
ABSTRACT:
SUBMITTER: Boyle KE
PROVIDER: S-EPMC2965170 | biostudies-literature | 2010 Mar
REPOSITORIES: biostudies-literature
Boyle Kristopher E KE MacMillan Karen S KS Ellis David A DA Lajiness James P JP Robertson William M WM Boger Dale L DL
Bioorganic & medicinal chemistry letters 20100202 6
The design, synthesis and evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]oxazolo[2,3-e]indol-4-one-6-carboxylate (COI) derivatives are detailed representing analogs of duocarmycin SA containing an oxazole replacement for the fused pyrrole found in the alkylation subunit. ...[more]