Ontology highlight
ABSTRACT:
SUBMITTER: Chanda PB
PROVIDER: S-EPMC5052114 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Chanda Prem B PB Boyle Kristopher E KE Brody Daniel M DM Shukla Vyom V Boger Dale L DL
Bioorganic & medicinal chemistry 20160426 20
The design, synthesis, and evaluation of methyl 1,2,8,8a-tetrahydrocyclopropa[c]imidazolo[4,5-e]indol-4-one-6-carboxylate (CImI) derivatives are detailed representing analogs of duocarmycin SA and yatakemycin containing an imidazole replacement for the fused pyrrole found in the DNA alkylation subunit. ...[more]