Targeting angiogenesis in childhood sarcomas.
Ontology highlight
ABSTRACT:
SUBMITTER: Bid HK
PROVIDER: S-EPMC3005857 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Angiogenesis and vasculogenesis constitute two processes in the formation of new blood vessels and are essential for progression of solid tumors. Consequently, targeting angiogenesis, and to a lesser extent vasculogenesis, has become a major focus in cancer drug development. Angiogenesis inhibitors are now being tested in pediatric populations whereas inhibitors of vasculogenesis are in an earlier stage of development. Despite the initial enthusiasm for targeting angiogenesis for treatment of ca ...[more]
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