Ontology highlight
ABSTRACT:
SUBMITTER: Nir G
PROVIDER: S-EPMC3030240 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Nir Guy G Lindner Moshe M Dietrich Heidelinde R C HRC Girshevitz Olga O Vorgias Constantinos E CE Garini Yuval Y
Biophysical journal 20110201 3
HU is a highly conserved protein that is believed to play an important role in the architecture and dynamic compaction of bacterial DNA. Its ability to control DNA bending is crucial for functions such as transcription and replication. The effects of HU on the DNA structure have been studied so far mainly by single molecule methods that require us to apply stretching forces on the DNA and therefore may perturb the DNA-protein interaction. To overcome this hurdle, we study the effect of HU on the ...[more]