Ontology highlight
ABSTRACT:
SUBMITTER: Brackley KI
PROVIDER: S-EPMC3059788 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Brackley Karen I KI Grantham Julie J
Cell stress & chaperones 20101002 2
CCT is a member of the chaperonin family of molecular chaperones and consists of eight distinct subunit species which occupy fixed positions within the chaperonin rings. The activity of CCT is closely linked to the integrity of the cytoskeleton as newly synthesized actin and tubulin monomers are dependent upon CCT to reach their native conformations. Furthermore, an additional role for CCT involving interactions with assembling/assembled microfilaments and microtubules is emerging. CCT is also k ...[more]