Degradable nitric oxide-releasing biomaterials via post-polymerization functionalization of cross-linked polyesters.
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ABSTRACT:
SUBMITTER: Coneski PN
PROVIDER: S-EPMC3070196 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
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Degradable nitric oxide-releasing biomaterials via post-polymerization functionalization of cross-linked polyesters.
Coneski Peter N PN Rao Kavitha S KS Schoenfisch Mark H MH
Biomacromolecules 20101018 11
The synthesis of diverse nitric oxide (NO)-releasing network polyesters is described. The melt phase condensation of polyols with a calculated excess of diacid followed by thermal curing generates cross-linked polyesters containing acid end groups. Varying the composition and curing temperatures of the polyesters resulted in materials with tunable thermal and degradation properties. Glass transition temperatures for the synthesized materials range from -25.5 to 3.2 °C, while complete degradation ...[more]
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