Ontology highlight
ABSTRACT:
SUBMITTER: Aranda JF
PROVIDER: S-EPMC3078064 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Aranda Juan F JF Reglero-Real Natalia N Kremer Leonor L Marcos-Ramiro Beatriz B Ruiz-Sáenz Ana A Calvo María M Enrich Carlos C Correas Isabel I Millán Jaime J Alonso Miguel A MA
Molecular biology of the cell 20110216 8
Membrane organization into condensed domains or rafts provides molecular platforms for selective recruitment of proteins. Cell migration is a general process that requires spatiotemporal targeting of Rac1 to membrane rafts. The protein machinery responsible for making rafts competent to recruit Rac1 remains elusive. Some members of the MAL family of proteins are involved in specialized processes dependent on this type of membrane. Because condensed membrane domains are a general feature of the p ...[more]