Ontology highlight
ABSTRACT:
SUBMITTER: Lee C
PROVIDER: S-EPMC3096933 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Virology 20110422 1
The hepatitis C virus (HCV) non-structural (NS) 5A protein plays an essential role in the replication of the viral RNA by the membrane-associated replication complex (RC). Recently, a putative NS5A inhibitor, BMS-790052, exhibited the highest potency of any known anti-HCV compound in inhibiting HCV replication in vitro and showed a promising clinical effect in HCV-infected patients. The precise mechanism of action for this new class of potential anti-HCV therapeutics, however, is still unclear. ...[more]