Ontology highlight
ABSTRACT:
SUBMITTER: Robin C
PROVIDER: S-EPMC3109535 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Robin Catherine C Ottersbach Katrin K Boisset Jean-Charles JC Oziemlak Aneta A Dzierzak Elaine E
Blood 20110317 19
CD41 expression is associated with the earliest stages of mouse hematopoiesis. It is notably expressed on some cells of the intra-aortic hematopoietic clusters, an area where the first adult-repopulating hematopoietic stem cells (HSCs) are generated. Although it is generally accepted that CD41 expression marks the onset of primitive/definitive hematopoiesis, there are few published data concerning its expression on HSCs. It is as yet uncertain whether HSCs express CD41 throughout development, an ...[more]