Ontology highlight
ABSTRACT:
SUBMITTER: Li Z
PROVIDER: S-EPMC3133967 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Li Zhaoxia Z Wu Feng F Brant Steven R SR Kwon John H JH
Journal of immunology (Baltimore, Md. : 1950) 20110420 11
CD4(+) memory T cells include the Th17 cell population, which has been shown to be implicated in autoimmune and inflammatory diseases. These memory T cells express higher IL-23R and produce more IL-17 compared with their naive counterparts. However, the molecular mechanisms that regulate IL-23R expression in human T cells are not completely understood. MicroRNAs play important roles in a wide range of biological events through posttranscriptional suppression of target mRNAs. In this article, we ...[more]