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ABSTRACT:
SUBMITTER: Tipton JD
PROVIDER: S-EPMC3138281 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Tipton Jeremiah D JD Tran John C JC Catherman Adam D AD Ahlf Dorothy R DR Durbin Kenneth R KR Kelleher Neil L NL
The Journal of biological chemistry 20110601 29
The diverse proteome of an organism arises from such events as single nucleotide substitutions at the DNA level, different RNA processing, and dynamic enzymatic post-translational modifications. This minireview focuses on the measurement of intact proteins to describe the diversity found in proteomes. The field of biological mass spectrometry has steadily advanced, enabling improvements in the characterization of single proteins to proteins derived from cells or tissues. In this minireview, we d ...[more]