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Continuous gas/liquid-liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination.

ABSTRACT: 4-Fluoropyrazole systems may be prepared by a single, sequential telescoped two-step continuous gas/liquid-liquid/liquid flow process from diketone, fluorine gas and hydrazine starting materials.

SUBMITTER: Breen JR

PROVIDER: S-EPMC3168861 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

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Continuous gas/liquid-liquid/liquid flow synthesis of 4-fluoropyrazole derivatives by selective direct fluorination.

Breen Jessica R JR Sandford Graham G Yufit Dmitrii S DS Howard Judith A K JA Fray Jonathan J Patel Bhairavi B

Beilstein journal of organic chemistry 20110802

4-Fluoropyrazole systems may be prepared by a single, sequential telescoped two-step continuous gas/liquid-liquid/liquid flow process from diketone, fluorine gas and hydrazine starting materials. ...[more]

PMID: 21915207

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