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Direct displacement of alkoxy groups of vinylogous esters by Grignard reagents.

ABSTRACT: The direct displacement of alkoxy groups from the ? position of aromatic and unsaturated esters and ketones is described. The reaction is chemo- and regioselective, displaying wide substrate scope.

SUBMITTER: Brockway AJ

PROVIDER: S-EPMC3180960 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature

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Direct displacement of alkoxy groups of vinylogous esters by Grignard reagents.

Brockway Anthony J AJ González-López Marcos M Fettinger James C JC Shaw Jared T JT

The Journal of organic chemistry 20110329 9

The direct displacement of alkoxy groups from the β position of aromatic and unsaturated esters and ketones is described. The reaction is chemo- and regioselective, displaying wide substrate scope. ...[more]

PMID: 21446670

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