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Pd-catalyzed allylative dearomatisation using Grignard reagents.

ABSTRACT: Pd-catalyzed allylative dearomatisation of naphthyl halides is shown to be feasible by employing Grignard reagents. The high reactivity of the nucleophile allows for fast reactions and low catalyst loading, while a plethora of successfully substituted compounds illustrate the broad scope. Five membered heteroaromatic compounds are also demonstrated to be reactive under similar conditions.

SUBMITTER: Boldrini C

PROVIDER: S-EPMC8577247 | biostudies-literature |

REPOSITORIES: biostudies-literature

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