Ontology highlight
ABSTRACT:
SUBMITTER: Stam FJ
PROVIDER: S-EPMC3231776 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Stam Floor J FJ Hendricks Timothy J TJ Zhang Jingming J Geiman Eric J EJ Francius Cedric C Labosky Patricia A PA Clotman Frederic F Goulding Martyn M
Development (Cambridge, England) 20111124 1
The spinal cord contains a diverse array of physiologically distinct interneuron cell types that subserve specialized roles in somatosensory perception and motor control. The mechanisms that generate these specialized interneuronal cell types from multipotential spinal progenitors are not known. In this study, we describe a temporally regulated transcriptional program that controls the differentiation of Renshaw cells (RCs), an anatomically and functionally discrete spinal interneuron subtype. W ...[more]