Target-specific capture enhances sensitivity of electrochemical detection of bacterial pathogens.
Ontology highlight
ABSTRACT: We report the concentration and purification of bacterial 16S rRNA by the use of a biotinylated DNA target-specific capture (TSC) probe. For both cultivated bacterial and urine specimens from urinary tract infection patients, TSC resulted in a 5- to 8-fold improvement in the sensitivity of bacterial detection in a 16S rRNA electrochemical sensor assay.
SUBMITTER: Patel M
PROVIDER: S-EPMC3232961 | biostudies-literature |
REPOSITORIES: biostudies-literature
ACCESS DATA