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Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus.


ABSTRACT: Bacillus subtilis induces expression of the gene ytnP in the presence of the antimicrobial streptomycin, produced by the Gram-positive bacterium Streptomyces griseus. ytnP encodes a lactonase-homologous protein that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus.

SUBMITTER: Schneider J 

PROVIDER: S-EPMC3255736 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature

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Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus.

Schneider Johannes J   Yepes Ana A   Garcia-Betancur Juan C JC   Westedt Isa I   Mielich Benjamin B   López Daniel D  

Applied and environmental microbiology 20111118 2


Bacillus subtilis induces expression of the gene ytnP in the presence of the antimicrobial streptomycin, produced by the Gram-positive bacterium Streptomyces griseus. ytnP encodes a lactonase-homologous protein that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus. ...[more]

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