Photoinitiated nitric oxide-releasing tertiary S-nitrosothiol-modified xerogels.
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ABSTRACT:
SUBMITTER: Riccio DA
PROVIDER: S-EPMC3288218 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
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Photoinitiated nitric oxide-releasing tertiary S-nitrosothiol-modified xerogels.
Riccio Daniel A DA Coneski Peter N PN Nichols Scott P SP Broadnax Angela D AD Schoenfisch Mark H MH
ACS applied materials & interfaces 20120118 2
The synthesis of a tertiary thiol-bearing silane precursor (i.e., N-acetyl penicillamine propyltrimethoxysilane or NAPTMS) to enable enhanced NO storage stability at physiological temperature is described. The novel silane was co-condensed with alkoxy- or alkylalkoxysilanes under varied synthetic parameters (e.g., water to silane ratio, catalyst and solvent concentrations, and reaction time) to evaluate systematically the formation of stable xerogel films. The resulting xerogels were subsequentl ...[more]
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