Ontology highlight
ABSTRACT:
SUBMITTER: Nagata T
PROVIDER: S-EPMC3808222 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Nagata Tomoyuki T Shibata Nobuto N Shinagawa Shunichiro S Nakayama Ritsuko R Kuerban Bolati B Ohnuma Tohru T Arai Heii H Nakayama Kazuhiko K Yamada Hisashi H
Dementia and geriatric cognitive disorders extra 20130907 1
<h4>Background</h4>Some polymorphisms of the neurotrophin family have previously been investigated as candidate genes for Alzheimer's disease (AD). In the present study, we examined whether neurotrophin-3 (NTF-3) polymorphisms are genetic risk factors in patients with AD.<h4>Methods</h4>From a sample of 507 subjects, we recruited 248 age-matched subjects divided into 2 groups: AD patients (n = 143) and normal controls (NCs) (n = 105). We identified 3 representative NTF-3 single nucleotide polymo ...[more]