Ontology highlight
ABSTRACT:
SUBMITTER: Krasovskiy A
PROVIDER: S-EPMC3359135 | biostudies-literature | 2009 Nov
REPOSITORIES: biostudies-literature
Krasovskiy Arkady A Duplais Christophe C Lipshutz Bruce H BH
Journal of the American Chemical Society 20091101 43
Mix in water, stir. That is all that is required in this new approach to sp(3)-sp(2) cross-couplings between an alkyl iodide and an aryl bromide, both potentially bearing functionality. They react under catalysis by Pd(0) in the presence of zinc powder, aided by a nonionic amphiphile, to give the alkylated aromatic. No organic solvents and no heating; just add water. ...[more]