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40-De-oxy-40(S)-iodo-rapamycin.

ABSTRACT: The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol-ecules are linked by O-H?O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra-molecular O-H?O inter-action also occurs.

SUBMITTER: Xie L

PROVIDER: S-EPMC3414270 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature

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40-De-oxy-40(S)-iodo-rapamycin.

Xie Lijun L Zuo Jian J Yang Guoxin G Zheng Congshen C Cheng Yuanrong Y

Acta crystallographica. Section E, Structure reports online 20120704 Pt 8

The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, forming C(8) chains propagating in [100]. A weak intra-molecular O-H⋯O inter-action also occurs. ...[more]

PMID: 22904803

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