Increasing materials' response to two-photon NIR light via self-immolative dendritic scaffolds.

ABSTRACT: Photoactivation using two photons of NIR allows non-invasive biological manipulation. We applied the principle of dendritic amplification to improve the materials' sensitivity to NIR light. Light induced uncaging or release of L-glutamic acid was 2.8 fold higher when incorporating 4-bromo-7-hydroxycoumarin (Bhc) with self-immolative dendrimers compared with Bhc directly conjugated to L-glutamic acid.

SUBMITTER: Fomina N 

PROVIDER: S-EPMC3421069 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature