Ontology highlight
ABSTRACT:
SUBMITTER: Silberstein AL
PROVIDER: S-EPMC3479317 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Silberstein Amanda L AL Ramgren Stephen D SD Garg Neil K NK
Organic letters 20120703 14
The alkylation of aryl sulfamates and carbamates using iron catalysis is reported. The method constructs sp(2)-sp(3) carbon-carbon bonds and provides synthetically useful yields across a range of substrates (>35 examples). The directing group ability of sulfamates and carbamates, accompanied by their low reactivity toward conventional cross-couplings, renders these substrates useful for the synthesis of polyfunctionalized arenes. ...[more]