Optogenetic control of transcription in zebrafish.
Ontology highlight
ABSTRACT:
SUBMITTER: Liu H
PROVIDER: S-EPMC3511356 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Optogenetic control of transcription in zebrafish.
Liu Hongtao H Gomez Gustavo G Lin Sophia S Lin Shuo S Lin Chentao C
PloS one 20121130 11
Light inducible protein-protein interactions are powerful tools to manipulate biological processes. Genetically encoded light-gated proteins for controlling precise cellular behavior are a new and promising technology, called optogenetics. Here we exploited the blue light-induced transcription system in yeast and zebrafish, based on the blue light dependent interaction between two plant proteins, blue light photoreceptor Cryptochrome 2 (CRY2) and the bHLH transcription factor CIB1 (CRY-interacti ...[more]
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