Ontology highlight
ABSTRACT:
SUBMITTER: Jarecki BW
PROVIDER: S-EPMC3539143 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Jarecki Brian W BW Makino Shin-ichi S Beebe Emily T ET Fox Brian G BG Chanda Baron B
Scientific reports 20130108
Voltage-gated ion channels are a class of membrane proteins that temporally orchestrate the ion flux critical for chemical and electrical signaling in excitable cells. Current methods to investigate the function of these channels rely on heterologous expression in living systems or reconstitution into artificial membranes; however these approaches have inherent drawbacks which limit potential biophysical applications. Here, we describe a new integrated approach combining cell-free translation of ...[more]