Ontology highlight
ABSTRACT:
SUBMITTER: Szendro IG
PROVIDER: S-EPMC3545761 | biostudies-literature | 2013 Jan
REPOSITORIES: biostudies-literature
Szendro Ivan G IG Franke Jasper J de Visser J Arjan G M JA Krug Joachim J
Proceedings of the National Academy of Sciences of the United States of America 20121224 2
To gauge the relative importance of contingency and determinism in evolution is a fundamental problem that continues to motivate much theoretical and empirical research. In recent evolution experiments with microbes, this question has been explored by monitoring the repeatability of adaptive changes in replicate populations. Here, we present the results of an extensive computational study of evolutionary predictability based on an experimentally measured eight-locus fitness landscape for the fil ...[more]