Ontology highlight
ABSTRACT:
SUBMITTER: Naidu S
PROVIDER: S-EPMC3566551 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Naidu Srivatsava S Friedrich J Karsten JK Russell Jackie J Zomerdijk Joost C B M JC
Science (New York, N.Y.) 20110901 6049
Transcription by eukaryotic RNA polymerases (Pols) II and III and archaeal Pol requires structurally related general transcription factors TFIIB, Brf1, and TFB, respectively, which are essential for polymerase recruitment and initiation events. A TFIIB-like protein was not evident in the Pol I basal transcription machinery. We report that TAF1B, a subunit of human Pol I basal transcription factor SL1, is structurally related to TFIIB/TFIIB-like proteins, through predicted amino-terminal zinc rib ...[more]