Ontology highlight
ABSTRACT:
SUBMITTER: Gupta R
PROVIDER: S-EPMC3580842 | biostudies-literature | 2010 Nov
REPOSITORIES: biostudies-literature
Gupta R R Ejebe K K Butler J J Lettre G G Lyon H H Guiducci C C Wilks R R Bennett F F Forrester T T Tayo B B Musunuru K K Hirschhorn J J Kathiresan S S Cooper R S RS McKenzie C A CA
Human genetics 20100914 5
The relevance of loci associated with blood lipids recently identified in European populations in individuals of African ancestry is unknown. We tested association between lipid traits and 36 previously described single-nucleotide polymorphisms (SNPs) in 1,466 individuals of African ancestry from Spanish Town, Jamaica. For the same allele and effect direction as observed in individuals of European ancestry, SNPs at three loci (1p13, 2p21, and 19p13) showed statistically significant association ( ...[more]