Ontology highlight
ABSTRACT:
SUBMITTER: Robinson GC
PROVIDER: S-EPMC3603450 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Robinson Graham C GC Bason John V JV Montgomery Martin G MG Fearnley Ian M IM Mueller David M DM Leslie Andrew G W AG Walker John E JE
Open biology 20130213 2
The structure of F₁-ATPase from Saccharomyces cerevisiae inhibited by the yeast IF₁ has been determined at 2.5 Å resolution. The inhibitory region of IF₁ from residues 1 to 36 is entrapped between the C-terminal domains of the α(DP)- and β(DP)-subunits in one of the three catalytic interfaces of the enzyme. Although the structure of the inhibited complex is similar to that of the bovine-inhibited complex, there are significant differences between the structures of the inhibitors and their detail ...[more]