Ontology highlight
ABSTRACT:
SUBMITTER: Jamieson K
PROVIDER: S-EPMC3625340 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Jamieson Kirsty K Rountree Michael R MR Lewis Zachary A ZA Stajich Jason E JE Selker Eric U EU
Proceedings of the National Academy of Sciences of the United States of America 20130325 15
Trimethylated lysine 27 on histone H3 (H3K27me3) is present in Drosophila, Arabidopsis, worms, and mammals, but is absent from yeasts that have been examined. We identified and analyzed H3K27me3 in the filamentous fungus Neurospora crassa and in other Neurospora species. H3K27me3 covers 6.8% of the N. crassa genome, encompassing 223 domains, including 774 genes, all of which are transcriptionally silent. N. crassa H3K27me3-marked genes are less conserved than unmarked genes and only ∼35% of gene ...[more]