Ontology highlight
ABSTRACT:
SUBMITTER: Kang KS
PROVIDER: S-EPMC3634098 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Kang Ki Soo KS Lee Naeun N Shin Min Sun MS Kim Sang Doo SD Yu Yinyi Y Mohanty Subhasis S Belshe Robert B RB Montgomery Ruth R RR Shaw Albert C AC Kang Insoo I
Clinical immunology (Orlando, Fla.) 20130315 2
Alterations in T cell immunity occur with aging. Influenza causes significant morbidity and mortality in the elderly. We investigated the relationship of serum IgG responses with hemagglutinin inhibition (HI) antibody titers and the frequency of distinct T cell subsets in young and elderly people who received the inactivated influenza vaccine. Influenza vaccine-specific IgG responses correlated with the increase of HI antibody titers and the frequency of CD4(+) T cells producing IFN-γ and IL-17 ...[more]