Ontology highlight
ABSTRACT:
SUBMITTER: Hutt OE
PROVIDER: S-EPMC3638842 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Hutt Oliver E OE Doan Trinh L TL Georg Gunda I GI
Organic letters 20130326 7
We have applied a diversity-oriented approach for the synthesis of skeletally diverse and stereochemically complex templates for small-molecule library production by performing Beckmann rearrangement and Beckmann fragmentation reactions on the bicyclo[3.2.1]octane rings of steviol and isosteviol, aglycones derived from the diterpene natural product stevioside. The optimization of these two reaction pathways is presented along with the successful application of a photo-Beckmann rearrangement. Thi ...[more]