Ontology highlight
ABSTRACT:
SUBMITTER: Brancaccio M
PROVIDER: S-EPMC3666084 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Brancaccio Marco M Maywood Elizabeth S ES Chesham Johanna E JE Loudon Andrew S I AS Hastings Michael H MH
Neuron 20130425 4
The role of intracellular transcriptional/post-translational feedback loops (TTFL) within the circadian pacemaker of the suprachiasmatic nucleus (SCN) is well established. In contrast, contributions from G-coupled pathways and cytosolic rhythms to the intercellular control of SCN pacemaking are poorly understood. We therefore combined viral transduction of SCN slices with fluorescence/bioluminescence imaging to visualize GCaMP3-reported circadian oscillations of intracellular calcium [Ca2+]i alo ...[more]