Ontology highlight
ABSTRACT:
SUBMITTER: Josefsson L
PROVIDER: S-EPMC3688524 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Josefsson Lina L Palmer Sarah S Faria Nuno R NR Lemey Philippe P Casazza Joseph J Ambrozak David D Kearney Mary M Shao Wei W Kottilil Shyamasundaran S Sneller Michael M Mellors John J Coffin John M JM Maldarelli Frank F
PLoS pathogens 20130620 6
Genetic recombination contributes to the diversity of human immunodeficiency virus (HIV-1). Productive HIV-1 recombination is, however, dependent on both the number of HIV-1 genomes per infected cell and the genetic relationship between these viral genomes. A detailed analysis of the number of proviruses and their genetic relationship in infected cells isolated from peripheral blood and tissue compartments is therefore important for understanding HIV-1 recombination, genetic diversity and the dy ...[more]