Ontology highlight
ABSTRACT:
SUBMITTER: Zaiss MM
PROVIDER: S-EPMC3731249 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Zaiss Mario M MM Maslowski Kendle M KM Mosconi Ilaria I Guenat Nadine N Marsland Benjamin J BJ Harris Nicola L NL
PLoS pathogens 20130801 8
Approximately 2 billion people currently suffer from intestinal helminth infections, which are typically chronic in nature and result in growth retardation, vitamin A deficiency, anemia and poor cognitive function. Such chronicity results from co-evolution between helminths and their mammalian hosts; however, the molecular mechanisms by which these organisms avert immune rejection are not clear. We have found that the natural murine helminth, Heligmosomoides polygyrus bakeri (Hp) elicits the sec ...[more]