Ontology highlight
ABSTRACT:
SUBMITTER: Wagley Y
PROVIDER: S-EPMC3733323 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Monoclonal antibodies in immunodiagnosis and immunotherapy 20130801 4
MUDENG (mu-2-related death-inducing gene, MuD) encodes a predicted ∼54-kDa protein in humans, considered to be involved in trafficking proteins from endosomes toward other membranous compartments as well as in inducing cell death. Here we report on the generation of a mouse monoclonal antibody (MAb) against the middle domain of human (h) MuD. This IgG sub 1 MAb, named M3H9, recognizes residues 244-326 in the middle domain of the MuD protein. Thus, the MuD proteins expressed in an astroglioma cel ...[more]