Ontology highlight
ABSTRACT:
SUBMITTER: Charbonneau B
PROVIDER: S-EPMC3758443 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Charbonneau Bridget B Wang Alice H AH Maurer Matthew J MJ Asmann Yan W YW Zent Clive S CS Link Brian K BK Ansell Stephen M SM Weiner George J GJ Ozsan Nazan N Feldman Andrew L AL Witzig Thomas E TE Cunningham Julie M JM Dogan Ahmet A Habermann Thomas M TM Slager Susan L SL Novak Anne J AJ Cerhan James R JR
Cancer immunology, immunotherapy : CII 20130628 9
CXCR5 [chemokine (C-X-C motif) receptor 5; also known as Burkitt lymphoma receptor 1 (BCR1)] is expressed on mature B-cells, subsets of CD4+ and CD8+ T-cells, and skin-derived migratory dendritic cells. Together with its ligand, CXCL13, CXCR5 is involved in guiding B-cells into the B-cell zones of secondary lymphoid organs as well as T-cell migration. This study evaluated the role of common germline genetic variation in CXCR5 in the risk and prognosis of non-Hodgkin lymphoma (NHL) using a clinic ...[more]