Ontology highlight
ABSTRACT:
SUBMITTER: Kim HN
PROVIDER: S-EPMC4013656 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
Kim Hee Nam HN Kim Nan Young NY Yu Li L Kim Yeo-Kyeoung YK Lee Il-Kwon IK Yang Deok-Hwan DH Lee Je-Jung JJ Shin Min-Ho MH Park Kyeong-Soo KS Choi Jin-Su JS Kim Hyeoung-Joon HJ
International journal of molecular sciences 20140421 4
The damage caused by oxidative stress and exposure to cigarette smoke and alcohol necessitate DNA damage repair and transport by multidrug resistance-1 (MDR1). To explore the association between polymorphisms in these genes and non-Hodgkin lymphoma risk, we analyzed 15 polymorphisms of 12 genes in a population-based study in Korea (694 cases and 1700 controls). Four genotypes of DNA repair pathway genes (XRCC1 399 GA, OGG1 326 GG, BRCA1 871 TT, and WRN 787 TT) were associated with a decreased ri ...[more]