Ontology highlight
ABSTRACT:
SUBMITTER: Salon J
PROVIDER: S-EPMC3763942 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Salon Jozef J Gan Jianhua J Abdur Rob R Liu Hehua H Huang Zhen Z
Organic letters 20130716 15
6-Se-guanosine phosphoramidite and RNAs have been synthesized by selenium substitution of the 6-oxygen atom, and it is revealed that the Se-derivatization is relatively stable and that bulge and wobble structures can better accommodate a large Se atom than a duplex. This Se-modification is useful in the structural study of RNAs and their protein complexes. ...[more]