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Platinum-catalyzed tandem indole annulation/arylation for the synthesis of diindolylmethanes and indolo[3,2-b]carbazoles.

ABSTRACT: Various diindolylmethanes were prepared from propargylic ethers and substituted indoles via a platinum-catalyzed tandem indole annulation/arylation cascade. The resulting diindolylmethanes could be converted to natural product malassezin by formylation or indolo[3,2-b]carbazoles by cyclization.

SUBMITTER: Shu D

PROVIDER: S-EPMC3776426 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature

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Platinum-catalyzed tandem indole annulation/arylation for the synthesis of diindolylmethanes and indolo[3,2-b]carbazoles.

Shu Dongxu D Winston-McPherson Gabrielle N GN Song Wangze W Tang Weiping W

Organic letters 20130805 16

Various diindolylmethanes were prepared from propargylic ethers and substituted indoles via a platinum-catalyzed tandem indole annulation/arylation cascade. The resulting diindolylmethanes could be converted to natural product malassezin by formylation or indolo[3,2-b]carbazoles by cyclization. ...[more]

PMID: 23909946

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