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Facile synthesis of indolo[3,2-a]carbazoles via Pd-catalyzed twofold oxidative cyclization.

ABSTRACT: A rapid and efficient route has been developed for the synthesis of 9-methoxycarbonylindolo[3,2-a]carbazole derivatives. The key steps in this approach involved an aromatic amination and an oxidative biaryl coupling. Via the present route, indolo[3,2-a]carbazole derivatives are available in 3-4 steps based on commercially available starting materials.

SUBMITTER: Yang C 

PROVIDER: S-EPMC5238593 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

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Facile synthesis of indolo[3,2-<i>a</i>]carbazoles via Pd-catalyzed twofold oxidative cyclization.

Yang Chao C   Lin Kai K   Huang Lan L   Pan Wei-Dong WD   Liu Sheng S  

Beilstein journal of organic chemistry 20161122

A rapid and efficient route has been developed for the synthesis of 9-methoxycarbonylindolo[3,2-<i>a</i>]carbazole derivatives. The key steps in this approach involved an aromatic amination and an oxidative biaryl coupling. Via the present route, indolo[3,2-<i>a</i>]carbazole derivatives are available in 3-4 steps based on commercially available starting materials. ...[more]

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