Ontology highlight
ABSTRACT:
SUBMITTER: Litchfield K
PROVIDER: S-EPMC4375409 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Litchfield Kevin K Sultana Razvan R Renwick Anthony A Dudakia Darshna D Seal Sheila S Ramsay Emma E Powell Silvana S Elliott Anna A Warren-Perry Margaret M Eeles Rosalind R Peto Julian J Kote-Jarai Zsofia Z Muir Kenneth K Nsengimana Jeremie J Stratton Michael R MR Easton Douglas F DF Bishop D Timothy DT Huddart Robert A RA Rahman Nazneen N Turnbull Clare C
Human molecular genetics 20141003 4
Recent genome-wide association studies (GWAS) and subsequent meta-analyses have identified over 25 SNPs at 18 loci, together accounting for >15% of the genetic susceptibility to testicular germ cell tumour (TGCT). To identify further common SNPs associated with TGCT, here we report a three-stage experiment, involving 4098 cases and 18 972 controls. Stage 1 comprised previously published GWAS analysis of 307 291 SNPs in 986 cases and 4946 controls. In Stage 2, we used previously published customi ...[more]