Ontology highlight
ABSTRACT:
SUBMITTER: Tu X
PROVIDER: S-EPMC3791271 | biostudies-literature | 2013 Oct
REPOSITORIES: biostudies-literature
Tu Xin X Nie Shaofang S Liao Yuhua Y Zhang Hongsong H Fan Qian Q Xu Chengqi C Bai Ying Y Wang Fan F Ren Xiang X Tang Tingting T Xia Ni N Li Sisi S Huang Yuan Y Liu Juan J Yang Qing Q Zhao Yuanyuan Y Lv Qiulun Q Li Qingxian Q Li Yue Y Xia Yunlong Y Qian Jin J Li Bin B Wu Gang G Wu Yanxia Y Yang Yan Y Wang Qing K QK Cheng Xiang X
American journal of human genetics 20130926 4
The effects of interleukin-33 (IL-33) on the immune system have been clearly demonstrated; however, in cardiovascular diseases, especially in coronary artery disease (CAD), these effects have not yet been clarified. In this study, we investigate the genetic role of the IL-33-ST2L pathway in CAD. We performed three-stage case-control association analyses on a total of 4,521 individuals with CAD and 4,809 controls via tag SNPs in the genes encoding IL-33 and ST2L-IL-1RL1. One tag SNP in each gene ...[more]