Ontology highlight
ABSTRACT:
SUBMITTER: Nakao M
PROVIDER: S-EPMC3798558 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Nakao Makoto M Hosono Satoyo S Ito Hidemi H Watanabe Miki M Mizuno Nobumasa N Sato Shigeki S Yatabe Yasushi Y Yamao Kenji K Ueda Ryuzo R Tajima Kazuo K Tanaka Hideo H Matsuo Keitaro K
Journal of epidemiology 20120728 6
<h4>Background</h4>Although several reports have described a possible association between DNA repair genes and pancreatic cancer (PC) in smokers, this association has not been fully evaluated in an Asian population. We assessed the impact of genetic polymorphisms in the base excision repair (BER) pathway on PC risk among Japanese.<h4>Methods</h4>This case-control study compared the frequency of 5 single-nucleotide polymorphisms (SNPs) of BER genes, namely rs1052133 in OGG1, rs1799782 and rs25487 ...[more]