Ontology highlight
ABSTRACT:
SUBMITTER: Ferdin J
PROVIDER: S-EPMC3824588 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Ferdin J J Nishida N N Wu X X Nicoloso M S MS Shah M Y MY Devlin C C Ling H H Shimizu M M Kumar K K Cortez M A MA Ferracin M M Bi Y Y Yang D D Czerniak B B Zhang W W Schmittgen T D TD Voorhoeve M P MP Reginato M J MJ Negrini M M Davuluri R V RV Kunej T T Ivan M M Calin G A GA Calin G A GA
Cell death and differentiation 20130913 12
Recent data have linked hypoxia, a classic feature of the tumor microenvironment, to the function of specific microRNAs (miRNAs); however, whether hypoxia affects other types of noncoding transcripts is currently unknown. Starting from a genome-wide expression profiling, we demonstrate for the first time a functional link between oxygen deprivation and the modulation of long noncoding transcripts from ultraconserved regions, termed transcribed-ultraconserved regions (T-UCRs). Interestingly, seve ...[more]