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Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles.

ABSTRACT: Gold(I) complexes have emerged as powerful and useful catalysts for the formation of new C-C, C-O and C-N bonds. Taking advantage of the specificity of [IPrAuNCMe][SbF6] complexes to favor the 5-exo-dig cyclization over the 6-endo-dig pathway, we report a high yielding and efficient method to generate substituted polyaromatic heterocycles under remarkably mild reaction conditions.

SUBMITTER: Morin M

PROVIDER: S-EPMC3869369 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature

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Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles.

Morin Mathieu M Levesque Patrick P Barriault Louis L

Beilstein journal of organic chemistry 20131122

Gold(I) complexes have emerged as powerful and useful catalysts for the formation of new C-C, C-O and C-N bonds. Taking advantage of the specificity of [IPrAuNCMe][SbF6] complexes to favor the 5-exo-dig cyclization over the 6-endo-dig pathway, we report a high yielding and efficient method to generate substituted polyaromatic heterocycles under remarkably mild reaction conditions. ...[more]

PMID: 24367426

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