Gold(I)-catalyzed domino cyclization for the synthesis of polyaromatic heterocycles.

ABSTRACT: Gold(I) complexes have emerged as powerful and useful catalysts for the formation of new C-C, C-O and C-N bonds. Taking advantage of the specificity of [IPrAuNCMe][SbF6] complexes to favor the 5-exo-dig cyclization over the 6-endo-dig pathway, we report a high yielding and efficient method to generate substituted polyaromatic heterocycles under remarkably mild reaction conditions.

SUBMITTER: Morin M 

PROVIDER: S-EPMC3869369 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature